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Description

J Pineal Res (2019) 66(2):e12547

Mixing two different peptide vials in the same syringe

Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders

In the current study, we apply a plethora of techniques, including NMR, HDX-MS, and native nano electrospray ionisation (ESI) MS to study the differences in the conformation of aggregation prone and non-aggregation prone monomeric aSyn including phosphorylated aSyn, pS129, and familial aSyn mutants, A30P, E46K, H50Q, G51D, A53T and A53E

A diferencia de las variantes modificadas con DAC, la forma Sin DAC se caracteriza por una ventana de actividad ms corta, lo que la convierte en un punto de inters en estudios sobre la dinmica de los pulsos endgenos de la hormona del crecimiento y los mecanismos de retroalimentacin regulatoria