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Using immunofluorescence techniques and other methods, our investigation into the expression trends of ferroptosis-related markers such as ASCL4 and GPX4 suggests that the effective intracellular delivery of nanomaterials may play a pivotal role in maintaining the stability of System xc-/Glutathione (GSH)/GPX4 axis, which in turn helps counteract the damage induced by UV radiation and preserves cell viability