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DHEAS functions as a critical neuroprotective and immunomodulatory buffer, antagonizing the suppressive effects of cortisol on Natural Killer (NK) cells and Th1-mediated immunity ( 6.3 Chronodisruption and the reprogramming of the endocrine network The shift from a rhythmic, steep cortisol slope to a flattened profile represents more than just a loss of timing

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By reframing neuroprotection as a systemic, multicellular endeavor, this review highlights the potential to not only extend life expectancy, but also preserve meaningful quality of life in individuals affected by neurodegenerative diseases

What works best: Inject evenings before days when you can rest

PMID: 122 PhilippouEPeterssonSDRodomarCNikiphorouE