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Ferroptosis and its potential role in the physiopathology of Parkinson's disease

Thank you, Phil, for your hard work, ingenuity, and dedication over the past two decades

doi: 10.1016/j.biopha.2018.09.058

Some studies also state the roles played by mitochondria and the TrpKYN system, their interactions and their involvement in preclinical and clinical research on serious neurological and psychiatric diseases [22]

It also improves immunological function

Affective disorders and depression are associated with high levels of oxidative stress markers [such as 8-hydroxydeoxyguanosine (8-OHdG)], proinflammatory cytokines (such as interleukins (IL) IL-1 and IL-6 and tumor necrosis factor alpha (TNF)), as well as with decreased levels of antioxidants (such as coenzyme Q10, glutathione peroxidase, and zinc) (Ng et al., 2008