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FIGURE 3 Hypermethylation of ADHFE1 (Alcohol dehydrogenase iron containing 1) promotes the proliferation of CRC cells by regulating cell cycle progression (Hu et al., 2019)

Neurogastroenterol Motil 23(8):697710 Taheri Y, Quispe C, Herrera-Bravo J, Sharifi-Rad J, Ezzat SM, Merghany RM, Shaheen S, Azmi L, Prakash Mishra A, Sener B (2022) Urtica dioica -derived phytochemicals for pharmacological and therapeutic applications

In summary, both ME/CFS caused by EBV or other pathogens, SARS-CoV-2-induced LC, and post-COVID-19 vaccine syndrome could follow a model of autoimmune disease development like that of ASIA syndrome, multiple sclerosis, or lupus erythematosus, but with a pattern of autoimmunity against the adenohypophysis ( Figure 3 )

Among those qualifying for sequencing, the proportions with persistent viremia progressively declined with time, with only 3 participants being persistently viremic by Year 8