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This is because the double bond near the bis -allyl methylene group in PUFAs can weaken the hydrogen bonding energy of the methylene group, resulting in its sensitivity to dehydrogenation and subsequent oxygenation ( Before the initiation of lipid peroxidation, intracellular free AA and AdA need to be inserted into the PLs on the cell membranes

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1991 Jul;14(7):598-604

10.1016/j.redox.2020.101494 Redox Biol

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