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In the Childhood Origins of Asthma (COAST) birth cohort a prospective study of 289 children at high atopic risk followed from birth to age 6 found that rhinovirus-induced wheezing illnesses in the first three years of life were the single strongest predictor of asthma at school age, regardless of aeroallergen sensitization or other risk factors

Heavy metal phytoavailability in a contaminated soil of northeastern Oklahoma as affected by biochar amendment

Embryos were dechorionated in 45% hypochlorite on a filter for 1 min followed by washing with flowing distilled water

Nevertheless, compared to other markers such as 8-OH-dG, fewer meta-analyses are available, possibly due to the difficulty to compare non-absolute results across studies, and due to the more complex analytical investigation

Funding This research is supported by the fund (20182021) of Tohoku University Hospital

Further analysis by Western blot showed that rhGPx3 mutant with excess amino acid could be recognized by the monoclonal antibody against the hexahistidine tag, but not in the case of the protein treated with factor Xa (Figure 1a and 1b)