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Interestingly, the AKT inhibitor, AKTi, inhibits SAL-mediated cell senescence in LNCaP cells, whereas inhibition of the MAPK pathway did not interfere with the SAL-mediated cell senescence [4], suggesting that the AR-AKT signaling mediates androgen-induced cell senescence

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[DOI] [PubMed] [Google Scholar] 145.Haines J., Haycraft E., Lytle L., Nicklaus S., Kok F.J., Merdji M., et al

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