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The enrichment of pathways associated with mitochondrial respiration and redox balance further supported a scenario of increased energetic and oxidative burden in lipedema tissue

Taylor A, Robson A, Houghton BC, Jepson CA et al (2013) Epididymal specific, selenium-independent GPX5 protects cells from oxidative stress-induced lipid peroxidation and DNA mutation

found that multiple abnormalities of palmitoylated proteins were present in PD patients, which were strongly associated with mitochondrial dysfunction, oxidative stress, and inflammation (226)

Nerve and tissue repair: Research shows GHK-Cu promotes neurite outgrowth and supports repair of nerve tissue, making it a candidate peptide for post-surgical or neuropathy-adjacent protocols

44 Jones et al

( Pharmaceuticals , 2026) reviewed BPC-157 in Achilles tendon repair and muscle-to-bone healing, with proposed mechanisms involving EGR-1 gene upregulationa transcription factor important in tendon and ligament repair