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It was observed that PDT can induce an increase of NF-kB and heat shock proteins (HSP-60 and HSP-70) 247,249,250

Given that DPCs can not readily enter the proteasomal 20S core, there are a few models for how it may contribute to DPC proteolysis

The slightly alkaline mitochondrial matrix and near-neutral cytosol may differentially favor deamination and amination reactions, linking GDH activity to subcellular compartmentalization and metabolic state

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Moodley et al

In a study, it has been reported that the GSH level in epileptic patients did not change compared to healthy individuals 28