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Polyglutamine-rich suppressors of huntingtin toxicity act upstream of Hsp70 and Sti1 in spatial quality control of amyloid-like proteins

Science 375 (6584), 9941000

in December 2024 the FDA's Pharmacy Compounding Advisory Committee voted against adding it to the final 503A bulks list, citing nonclinical toxicity, an unresolved cardiac signal, and immunogenicity risk

If your medication is prohibited, then you might need to apply for a Therapeutic Use Exemption

Research Applications (Wolverine Blend Benefits) While BPC-157 and TB-500 are still under investigation and not approved for therapeutic use, preclinical studies have explored their potential in a range of biological contexts

doi:10.3390/biom13020294