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Kamen DL, Aranow C

In contrast, activation of adenosine A 2A receptors tends to facilitate synaptic transmission, particularly in the hippocampus [343, 344]

We therefore resorted to changing the reactivity of the MG core by removing the indole double bond (2,3- bond in indole numbering) by either reduction or oxidation, or oxidation followed by rearrangement (Fig