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Extracellular vesicle-packaged lncRNA from cancer-associated fibroblasts promotes immune evasion by downregulating HLA-A in pancreatic cancer

This oxidative stress can damage cells and contribute to various diseases and the aging process

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sudden cardiac death due to arrhythmias Treatment: Management for HC ingestion is supportive (no specific antidotes are available) Observe patients in a monitored setting for signs of respiratory distress Cardiac monitor and pulse oximetry are recommended Patients who show signs of impending respiratory failure, despite supplemental oxygen, may require rapid intubation & ventilation Decontamination of the GI tract generally is not recommended because of the risk of aspiration and the low GI toxicity of most HCs Indicated medications include dextrose, thiamine, and naloxone for altered mental status and albuterol for bronchospasm Notes: The American Association of Poison Control Centers lists HCs as the 12th most common poison exposure In 1997, 3% of cases reported to US poison control centers involved HC exposure

Itzkovitz, D

The Rag complex is in turn tethered to the lysosomal membrane via another multi-subunit complex called Ragulator that interacts with the lysosomal V-ATPase and the amino acid transporter SLC38A9 71,72