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Pergola defines a crucial result

It also increases the likelihood of developing hypertension, kidney damage, albuminuria, and chronic kidney disease (CKD), ascribed to the death of nephrons and subsequent hyperfiltration in the surviving nephrons (50, 51)

From a metabolic point of view, during exercise at 50% O 2 max intensities or below, fatty-acid oxidation is the most predominant source of energy, whereas, during exercise of moderate intensity (between 50 and 70% O 2 max ), the energy source is provided by both fatty acids and glucose, with a gradual increase in the intensity [51]

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Funding The authors received no external financial support for the research, authorship, or publication of this article