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There is also a theoretical concern regarding nutritional status

The Prox1-Vegfr3 feedback loop maintains the identity and the number of lymphatic endothelial cell progenitors

demonstrated that curcumin can potentiate ionizing radiation-induced death of glioma cells via activation of the endoplasmic reticulum (ER) stress PERK-eIF2 and IRE1-XBP1 signaling pathwaysa finding corroborated in murine models (86)

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