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[DOI] [PubMed] [Google Scholar] Debes F, Budtz-Jorgensen E, Weihe P, White RF, Grandjean P

AIM2 activation has been linked to the production of IL-1 and other inflammatory mediators, which can perpetuate neuroinflammation and impair neurotransmitter systems [140,142]

Furthermore, an 8-week trial on patients with fatty liver disease showed that 1,000 mg/day of the oil significantly reduced serum levels of hs-CRP and malondialdehyde (MDA), a primary marker of lipid peroxidation and oxidative stress

Biological Trace Element Research, 200 (5), 25282548

COX-2 is less sensitive to aspirin because inhibition of the inducible COX-2 requires higher doses of aspirin and shorter dosing intervals as nucleated cells can promptly resynthesise the enzyme