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218 Importantly, in vivo administration of a singledose of TDI11861 to male mice was shown to block the bicarbonateinduced cAMP accumulation and protein phosphorylation in epididymal mouse sperm cells, resulting in the loss of motility approximately 15 min after the treatment

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However, the bioactivities of SeNPs need further investigations to confirm their bioactivities and application potentials in the cryopreservation of bull semen

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