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TMP can simultaneously reduce the production of IL-2, IL-6, and TNF- to counter pentaerythritol-induced epileptic seizures in experimental rats ( A few coumarins have also been studied in vivo in epilepsy patients

The authors of a Cochrane Review on this topic have concluded that supplements of vitamin B12 alone or with other B vitamins do not prevent heart attacks or reduce heart-related death rates (1)

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