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Chan, S

Ghio, A

As the waterfall retreats a deep gorge with steep U-faced sides forms down the length of the river and marks the length of retreat

Biochem J 62 : 315323 Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

doi:10.1038/288715a0

This underscores the importance of obtaining hormetins from whole foodswhere they exist in naturally moderate concentrationsrather than from high-dose supplements, and it highlights why a deep understanding of the full dose-response curve is essential for both food safety and functional food design