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Principles underpinning the use of new methodologies in the risk assessment of cosmetic ingredients

Choi, J

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Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1

Pre-clinical studies demonstrated that KD and D-BHB protect neurons, improve mitochondrial function, and enhance ATP production particularly in models characterized by mitochondrial dysfunction and degeneration of dopaminergic neurons, which are hallmark pathological features of PD [39, 83]

However, relying on sunshine alone is often insufficient to achieve optimal blood levels of vitamin D