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Moreover, animal models data strongly agree that overexpression of -syn leads to a direct insult to the dopaminergic system, reported as a decrease in tyrosine hydroxylase (TH) activity and expression within the striatum [36]

showed that LC3-I to LC3-II conversion, which is normally decreased during aging, was increased in mice with skeletal muscle-specific overexpression of IGF-1 [65]

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Whole cells are labelled via click chemistry and visualized using super-resolution microscopy, revealing higher resolution PG structural details and allowing the cell wall biosynthesis, as well as its destruction in immune cells, to be tracked

Karaa, A., Thompson, K