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Given that mast cell activation may be the first responder to injury (Jin et al., 2009b), and not the microglia, inhibition of mast cell activation may inhibit the pro-inflammatory cascade and therefore protect against neuroinflammation

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2025;64:e202501857

ramified cells) beneath these macrophages remain intact

It has quality-of-life applications related to skin health, as research supports its ability to tighten loose skin, improve skin firmness, reduce photodamage, promote wound healing, and more.41 Insulin: Insulin is a quality-of-life treatment for managing blood sugar

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