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Caro JF, Poulos J, Ittoop O, Pories WJ, Flickinger EG, Sinha MK: Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver

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( Reference Houglum, Venkataramani and Lyche 59 ) , in a series of six patients with chronic hepatitis C refractory to IFN therapy, showed that treatment with vitamin E inhibited important steps in hepatic fibrogenesis such as stellate cell activation and collagen-1(I) gene expression, suggesting a potential role of this vitamin in preventing hepatic fibrosis, which is a critical step in the progression of HCV-related liver disease

LSD1 inhibition promotes epithelial differentiation through derepression of fate-determining transcription factors

Immunotherapies, particularly immune checkpoint inhibitors, have taken the concept of treating cancers to the next level, by targeting the cancer patients immune cells rather than their cancer cells

Increases in plasma conjugated bilirubin lead to tea-colored urine, because conjugated bilirubin is water soluble