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Tm values were taken as the midpoint of the melting curves, found from the peak of the first derivative

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The therapy completely eliminated circulating B cells as well as pathogenic autoantibodies, and both patients experienced improved disease-related symptoms

c) Enrichment with 25 nM BG-LNA (20mer) over 25 nM BG-MOE (20mer)

Protect reconstituted solutions from light exposure using amber vials or storage in dark conditions