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Respir Med 107(6):911918

doi: 10.1016/j.yrtph.2018.03.019 145

Because of the high amount of lipids in the brain, intense oxygen consumption and increased oxidative metabolism show us that the brain is sensitive to oxidative stress

Among them, VNN1 (vascular non-inflammatory molecule 1) encodes an extracellular enzyme with pantothenate hydrolase activity, and related studies have reported that the metabolic pathway catalysed by the VNN1 pantothenate hydrolase can effectively inhibit the progression of respiratory IAV infection 36