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Periodic oxaliplatin administration in synergy with PER2-mediated PCNA transcription repression promotes chronochemotherapeutic efficacy of OSCC

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Phosphorylated 4E-BP1 releases cap-binding protein eukaryotic translation initiation factor 4E (eIF4E), which counteracts inhibition of protein synthesis by enabling eIF4E to form the eIF4F complex and to participate in cap-dependent translation [37, 38]

N.MerelloM.et al