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This effect could be attributed to the inclusion of positively charged BER within the lipid bilayer, enabling interactions with negatively charged phospholipids

Despite the pharmacokinetic challenges posed by the low systemic bioavailability of key withanolides in human plasma, their substantial in vivo effectiveness seems to result from multiple interconnected mechanisms

The limited number of epidemiological studies available have not identified drug-associated risks of major birth defects, miscarriage or other adverse maternal or fetal outcomes

10.3390/ijms21249735 94 ReynoldsA

29 Chen-RoetlingJ.ReganR

K., Schrauwen-Hinderling, V