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Validating the pertinence of our strategy, among the top-ranked compounds, we found molecules reported to promote oligodendrogenesis, including liothyronine (thyroid hormone), clemastine 23,55 , clomipramine 56 , piperidolate 57 , luteolin 58 , ifenprodil 59 , and propafenone 60

One of the most pressing limitations is the lack of PET tracers capable of reliably distinguishing between neurotoxic (pro-inflammatory) and neuroprotective microglial phenotypes in vivo

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Specific relevance to your goals is evaluated by your provider

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Wnt/-catenin is also a potential therapeutic target for common but refractory diseases such as psoriasis, viral infections, and obesity