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The bioactive compounds modulate cell activity through selective actions on the intracellular signaling pathways of various components, particularly cytokines and proinflammatory proteins, which play important cellular functions (Miguel et al., 2014)

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Nutrients 15 (11), 2493

38 Collectively, all these discoveries have contributed not only to our understanding of the biological aging process, but also allowed to develop rationale intervention strategies to target molecular hallmarks of this process and biomarkers to quantify biological aging status, aiming to achieved healthy lifespan extension with precise and multitargeted approaches

The hypothalamic-pituitary-adrenocortical system (HPA) plays a significant role in the cause and development of depression [131]