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RSL3 binds to the nucleophilic active site of GPX4, and then reduces the expression level of GPX4 most effectively through chloroacetamide moiety (Jelinek et al., 2018), thus inactivating GPX4, producing lethal ROS accumulation and inducing ferroptosis

Colloca, L

The absence of IRG1 exacerbates bone loss in a mouse model of ovariectomy-induced osteoporosis by increasing osteoclastogenesis through the potentiation of NLRP3 inflammasome activation

Epilepsy Res 167:106454

On Ishigaki Island, which has been selected as a "starry sky protected area, Star gazing tour The night tours are a must-see

This phenotypic plasticity is particularly evident in the penumbra, where the balance between pro-inflammatory and pro-regenerative signaling influences whether tissue undergoes delayed degeneration or functional recovery