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TNF-, COX-2, and p-NFB are prototypic pro-inflammatory cytokines because of their important role in initiating the cascade of cytokine activation and growth factors in the inflammatory response ( For further confirmation, ELISA was carried out to quantify the inflammatory markers of TNF-, p-NFB, and PGE 2

2008;31(9 Suppl):611

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Although concurrent short-term KD did not rescue cMPC1 / hearts from rapid decompensation and early mortality after pressure overload, 3 weeks of the KD before transverse aortic constriction is sufficient to rescue this phenotype

Mice were euthanized by intraperitoneal injection of 10 L/g of a ketamine-xylazine anesthetic combination in saline (300:30 mg/kg, respectively)

Additionally, increasing the success rate of therapeutic interventions will require the use of biomarker-guided therapy, such as QSM-MRI for patient stratification in clinical trials