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BBB disruption may enhance the unwanted effect of peripheral-derived factors, and Erion et al

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Insulin resistance Insulin resistance is the most common and widespread molecular mechanism of diabetic complications, not only in the high glucose state with extensive activation of insulin receptor signaling pathways, such as the regulation of glucose uptake by GLUT

However, the digestive systemas an important physiological organ systemincludes a wide range of organs like the esophagus, stomach, small intestine, colon, rectum, liver, biliary tract, and pancreas

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Microbes play a crucial role in supporting the development of a normal immune system