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Am J Respir Crit Care Med (2017) 195(6):80113

188,193 HSPs in chemotherapy and radiotherapy resistance HSPs in chemotherapy resistance HSPs play a critical role in mediating resistance to chemotherapy and radiotherapy

The underlying molecular mechanism and identification of transcription factor markers for laryngeal squamous cell carcinoma

Nat Med 19:202208 Spicer J, Marabelle A, Baurain JF, Jebsen NL, Jossang DE, Awada A, Kristeleit R, Loirat D, Lazaridis G et al (2021) Safety, antitumor activity, and T-cell responses in a dose-ranging phase I trial of the oncolytic peptide LTX-315 in patients with solid tumors

While synergism and additivity allow for achieving better effects with lower drug concentrations, clinical data suggest that independent drug action can also significantly improve patient outcomes (69)