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The B12-IF complex is absorbed by cells in the final section of the small intestine (the ileum), where IF is cleaved from B12 and subsequently, B12 passes into the blood where transport proteins bind to it and is distributed to cells all around the body (Obeid et al., 2015

The mRNA levels of CCL2 (C-C Motif Chemokine Ligand 2), CCL11 (C-C Motif Chemokine Ligand 11), CSF2 (Colony Stimulating Factor 2), CXCL10 (C-X-C Motif Chemokine Ligand 10), HGF (Hepatocyte Growth Factor), IL1RA (Interleukin 1 Receptor Antagonist), IL6 (Interleukin 6), IL10 (Interleukin 10), IL31 (Interleukin 31), LIF (LIF Interleukin 6 Family Cytokine), and NGF (Nerve Growth Factor) were quantified using specific primers in SYBR Green (Thermo Fisher) or TaqMan (Thermo Fisher) platforms following the manufacturers instructions

Eur J Endocrinol 158:153161

Therefore, mutations in the TNSALP gene result in a decrease in hydroxyapatite production, leading to impaired bone mineralization and decreased bone mass [41]

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2014, Nature) i obecna w komrkach satelitarnych mini std kierunki bada nad metabolizmem energetycznym adipocytw, gospodark NAD i regeneracj miniow