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[15] Inside the lysosome, transcobalamin is degraded and free cobalamin is exported to the cytosol, where a trafficking and processing protein encoded by MMACHC (with a partner encoded by MMADHC ) strips off whatever upper-axial ligand the incoming cobalamin carried cyanide, hydroxyl, methyl, or adenosyl and reduces the cobalt center

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doi:10.3390/nu12082184

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