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Furthermore, approximately 30% of these patients could be over-diagnosed using these tests, indicating the need for caution making treatment decisions

PMID: 16502665

doi:10.1016/j.watres.2012.06.017 Cherrak R, Hadjel M, Benderdouche N et al (2016) Treatment of recalcitrant organic pollutants in water by heterogeneous catalysis using a mixed material (TiO2-diatomite of Algeria

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In acute gout, MSU crystals, liberated from tissue deposits by remodeling effects or microtrauma, stimulate inflammatory cascades that involve complement activation and assembly of the C5b-9 membrane attack complex, and release of multiple inflammatory cytokines, including IL-1 and the chemokines IL-8 (CXCL8) and GRO- (CXCL1)

They work as a direct reactive oxygen species scavenger and as a source of sulfhydryl groups