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299 Studies in allergic diseases have shown that mTOR is a key molecule for sensing the immune microenvironment and determining the function and differentiation of immune cells, 300 because it regulates a variety of immune cells and limits pro-inflammatory mediators

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The review highlights functional complementarity rather than simple trade-offs: flavonoids predominantly buffer abiotic stress and mediate signaling, whereas anthraquinones provide high-intensity antimicrobial, antiherbivore, and allelopathic defenses, often acting through phototoxicity and soil-active residues

There is evidence to indicate that oxidative stress induces the SSG of -synuclein, which alters its conformational stability and promotes pathological oligomerization (75)

Jasmonate signaling is a well-established upstream driver of flavonoid/anthocyanin regulation through JAZ-centered repression modules that interface with MBW-controlled genes, while simultaneously modulating chromatin states at key regulators (Hichri et al., 2011