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4.3 Copper overload triggers pyroptosis Pyroptosis is a form of programmed cell death induced by inflammasomes that can clear damaged cells, but unlike apoptosis, it can trigger surrounding inflammatory reactions

(2) from arcade 1 to the next arcade (arcade 2), middle arcade inside ligations (or previous ligation) (1-2, Figures 2, 5-8, 21 and 22)

6.3 Role of polyphenols on athlete health One advantageous outcome of addressing the athletes nutritional requirements is enhancing athletic performance

Exercise induces radical production and the resultant exercise-induced oxidative stress in skeletal muscles impairs muscle force production and contributes to muscle fatigue during prolonged endurance exercise (Reid, 2008)