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While allergy awareness and education has improved, emergency department visits for anaphylaxis [2] and fatality from severe allergic reactions has not, and therefore the identification of treatments and interventions is a dire unmet need

cofactors may be metal enzymes, vitamins, coenzymes, or prosthetic groups

Declaration of interest: B

Supporting GSH levels through nutritional strategies N-acetylcysteine (NAC) as a cysteine precursor, glycine-rich foods, liposomal glutathione is a practical clinical consideration for women who are GSTM1 or GSTT1 null and facing high reactive estrogen metabolite burden

In some embodiments, the mitophagy stimulant causes autophagic elimination of mitochondria