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The effect is localized and temporary, meaning the surrounding muscles continue to function normally while the treated areas gradually return to baseline

a programmable drug delivery system which is composed of a chondroitin sulfate hydrogel shell and hydrophobic cores was built for delivering anti-tumor drugs into drug-resistant cancer cells and keeping effective drug concentration to sensitizing cancer cells to anti-cancer drugs by down-regulation of the anti-apoptosis protein Bcl-xl [146]

Mycophenolate mofetil is recommended as the preferred second-line therapy by both the American Association for the Study of Liver Diseases (AASLD) and ESPGHAN [29, 42]

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