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Side effects and safety profile If clinical efficacy is where semaglutide dominates, safety is where AOD 9604 makes its strongest case

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The pharmacology in animal studies and early human studies supported this design: AOD-9604 stimulates lipolysis and inhibits lipogenesis through activation of beta-3 adrenergic receptors in adipose tissue, without producing the IGF-1 elevation or insulin resistance signal that exogenous GH produces

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There is a risk with all injections such as bruising, infection, allergic reactions, and vascular occlusion

Besides the main differential characteristics, other negative findings to rule out common causes of true TMA, such as TTP, HUS, DIC, drug-induced TMA, autoimmune-associated TMA, etc., are also essential to guide primary specific management