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Bevacizumab, a humanized monoclonal antibody targeted against VEGF, was coupled with standard chemotherapy in a randomly selected phase 3 study of first-line therapy of metastatic colorectal cancer (CRC) [48]

doi: 10.1016/S0140-6736(04)17445-X 67

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Drug Metab Dispos 25(12):13291336 Jerjes W, Upile T, Shah P, Nhembe F, Gudka D, Kafas P, McCarthy E, Abbas S, Patel S, Hamdoon Z, Abiola J, Vourvachis M, Kalkani M, Al-Khawalde M, Leeson R, Banu B, Rob J, El-Maaytah M, Hopper C (2010) Risk factors associated with injury to the inferior alveolar and lingual nerves following third molar surgery-revisited

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Mechanizm dziaania i waciwoci BPC-157 ARG dziaa wielotorowo, angaujc kilka kluczowych szlakw biologicznych odpowiedzialnych za napraw i ochron tkanek: Stymulacja angiogenezy peptyd aktywuje szlak receptora VEGFR2 (receptor czynnika wzrostu rdbonka naczyniowego), co prowadzi do tworzenia nowych naczy krwiononych w obszarach uszkodzonych