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The NAD+ precursor nicotinamide riboside rescues mitochondrial defects and neuronal loss in iPSC and fly models of Parkinsons disease

Acute alcohol intoxication increases allopregnanolone, a potent GABAergic modulator, in a variety of brain regions including the hippocampus implicating the release of allopregnanolone as a potential mechanism of acute alcohol associated cognitive deficits (Tokunaga et al., 2003