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Although median levels were numerically lower in SA compared with M/M, there were no differences in BAL fluid GSSG or GSH:GSSG between M/M and SA

Multiple etiological hypotheses have been proposed, including intoxication with mycotoxins or environmental toxins (31, 32), viral infection, and trace element deficiency caused by a monotonous diet lacking minerals or vitamins (32), such as magnesium, iron, or thiamin (Figures 3AC) (33)

Moreover, the multidrug resistance protein-1 (MDR1, ABCB1), which transports organic cations, and the multidrug resistance protein-2 (MRP2, ABCC2), which regulates the independent flow of bile salts by excreting glutathione are involved [20]

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FCP, fecal calprotectin