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**Struktur Kulit:** Sebagai komponen utama penyusun kulit, kolagen berperan menjaga kekuatan dan fungsinya

While several side effects are associated with isotretinoin treatment, recent research has demonstrated that the mental health problems and gastrointestinal diseases that were believed to be associated with the drug may not be caused by Accutane

Redox Biol (2021) 45:102045

These chemical mediators can affect multiple organ systems including the respiratory, circulatory, integumentary, digestive, muscular and nervous system

In the colon, only a few macrophages were observed in the submucosal layer on the 3rd day after DSS treatment, but on the 5th day, many macrophages were observed in the mucosal and the submucosal layer where the colon plicae had collapsed (Fig

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