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To clear histamine from the body, particularly in the central nervous system, the body relies on an enzyme called Histamine N-Methyltransferase (HNMT)

Landgren CO, Chari A, Cohen YC, Spencer A, Voorhees P, Estell JA, et al

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Mild reactions can include temporary injection site redness and occasional headaches

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Subcutaneous injection achieves near 100% bioavailability and delivers consistent plasma concentrations, allowing researchers to establish reproducible dose-response relationships