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Because IGFBP-3 also carries IGF-1, when IGF-1 is administered on its own, the carrier IGFBP-3 saturates with IGF-1 displacing IGF-2 and thus augments its free circulating concentration

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in the 100 mg dose present here, serious GI effects are uncommon, but mild nausea or stomach discomfort could occur in sensitive patients

Instead, investigators believe it may influence: cellular metabolism adipocyte function energy utilization This distinguishes it from GLP-1 receptor agonists

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