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LL5 (LL5 in some cells) is a cytoplasmic protein that associates with the cell cortex through the interaction of its Pleckstrin homology (PH) domain with the phospholipid, PI(3,4,5)P3 [75]

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Franco et al suggest that GSH depletion may promote ROS generation and initiate apoptotic cell death processes

Recent studies have demonstrated the cell deaths role in the homeostasis of the intestinal epithelium in IBD (137)