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Mathieu F, Begaux F, Lan ZY, Suetens C, Hinsenkamp M

However, as the development and testing of remyelination-based therapies requires effective model systems with sustained demyelination and lack of complete endogenous remyelination, we conclude that 1 mM CPZ treatment of brain slice cultures is not a viable ex vivo model for these studies, however, could prove to be useful in acute demyelination studies, pending further characterization

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In addition to repairing the damage caused to the nerve, you may need to take additional steps to treat related pain, as well

Plasma levels decline significantly with age from approximately 200 ng/ml at age 20 to roughly 80 ng/ml by age 60