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FIGURE 3 IL-13 DRIVEN INFLAMMATION IS UNAFFECTED BY GGsTop, BUT INDUCTION OF MUCOUS EXPRESSION IS ATTENUATED Compared to control lung, exposure to IL-13 induced the level of lung mRNA transcript expression for IL-33 by sixfold ( Figure 3B ) and recruited eosinophils to the lung in the absence ( Figure 3C ) and presence ( Figure 3D ) of GGsTop

It inhibits the activation of the transcription factor NF-B, reducing the production of pro-inflammatory cytokines (IL-1, TNF-, IL-6) and inflammatory mediators (PGE2, NO)

Endocrine and metabolic causes: Thyroid disease, uncontrolled diabetes, polycystic ovary syndrome (PCOS), and luteal phase defects affect hormone balance needed to sustain pregnancy

A., Williams, L., Bork, P., Bridge, A., Gough, J., Haft, D

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